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1 - Slang term for the drug methaqualude or simple quaaludes, a barbituate like Central Nervous depressant drug which causes clumsiness and fatigue, often used to treat insomnia and anxiety.

2 - "TO BE ON LUDES": Idiotical, Dull Minded, Dim-Witted, Stupid, Lacking intelligence, Feeble Minded.
1 - My doc recommended i take ludes for my insomnia, there illegal but TS.

2 - WTF?? Are you on ludes mate? dont you know what im getting at? you cant even follow the simplist of instructions cant you?
by Brother Number One August 22, 2005
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its a tranq from long ago
"ludes man FUCKING ludes!!! call up the ludes dude dude and get some fucking ludes"
by Tarryn November 27, 2004
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Vitamin Q, Quakers, Quas, Q's, Disco Biscuits, Mandies,
Lemmons, Wallbangers, Quacks. Real name Methaqualone. A drug synthesized back in 1951 in India by two men named Indra Kishore and Hussain Zaheer. Was commonly used at clubs back in the 60's and 70's at discos (hence the name "Disco Biscuits") to make you feel better while you danced and partied. There were also special bars where they would serve non alcoholic beverages to cater to the people who used it. Now in decline due to it being declared a Schedule 1 substance.
Ludes used to be the one and only college past time.
by Matt the stud June 19, 2010
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Vitamin Q, Quakers, Quas, Q's, Disco Biscuits, Mandies,
Lemmons, Wallbangers, Quacks. Real name Methaqualone. A drug synthesized back in 1951 in India by two men named Indra Kishore and Hussain Zaheer. Was commonly used at clubs back in the 60's and 70's at discos (hence the name "Disco Biscuits") to make you feel better while you danced and partied. There were also special bars where they would serve non alcoholic beverages to cater to the people who used it. Now in decline due to it being declared a Schedule 1 substance.
Ludes used to be the one and only college past time.
by jkiller212 June 11, 2010
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Light Nudes, social media tolerated level of nudes. Naughty but won’t get you fired.
He asked for nudes but I’m saving the good ones for later, so I sent him a few Ludes instead.
by Naughty Mouth January 20, 2021
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n. 1. Quaaludes
2. what you take when you don't have shit else
What kind of shit you got? I ain't got shit, let's get some fucking ludes or some shit
by jimmy ivory April 2, 2004
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that mistake made me so pissed off i had to take some ludes to cool down.
by Pubert Qubert Quakenbusch April 3, 2003
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