One word with so many facets, meanings, and applications. This is not an attempt to cover them all, but merely one of them. Anyway,
one facet of it can be used in the context of describing someone or possibly a group of
people that gets severely taken advantage of, or totally screwed in some way, shape, or
fashion.
1. The motherfucker that gets THAT used
car is in for a big surprise....
2. Hear about that Tornado?....A whole lot of motherfuckers don't have a place to stay...
3. Those victims of the Haiti earthquake, Those
Poor motherfuckers are in some deep dogshit now