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losing my religion 

it literally means "losing my temper" or "going insane" to some degree. If you would look at the REM lyrics to the song by the same name, it makes more sense, it really has nothing to do with religion.
I was pretty much losing my religion after being forced to listen to rap music by all the freshman girls at my school.

losing my religion 

"I'm sick of everyone, I'm losing my religion"

Losing my Religion 

1. a southern slang phrase that means "flying off the handle", losing ones cool and losing ones self-control. Some people also think it could mean to get laid.

2. a big 1991 hit song from the Georgia rock band R.E.M..
1. George: Jeremy has been acting funny since he polished off a bottle of Wild Turkey.

Billy: Yep, he's lost some of his religion.

2. The title Losing My Religion caused some confusion at first here in the MidWest.

losing my religion 

1. a southern slang phrase that means "flying off the handle", losing ones cool and losing ones self-control. Some people also think it could mean to get laid.

2. a big 1991 hit song from the Georgia rock band R.E.M..
1. George: Jeremy has been acting funny since he polished off a bottle of Wild Turkey.
Billy: Yep, he's lost some of his religion.

2. The title "Losing My Religion" caused some confusion at first here in the MidWest.

losing my religion 

A southern expression for losing your temper.

Losing patience.
Losing your faith.

In someone or something.
WOOO GURL I AM LOSING MY RELIGION IF THAT THERE BOI DONT PLANT THOSE WATERMELONS RIGHT!!!!
losing my religion by AlanaLii March 14, 2012

losing my religion 

Must i really point out the obvious?!

you're losing faith in whatever bullshit u believe in.
Oh fuck, i just got hit by a truck. Thanks god - im now losing my religion