southern term for losing one's temper, "flying off the handle", etc. Note that the R.E.M. song of this title has nothing to do with religion, despite the common misinterpretation of the phrase.
"I was close losing my religion with the kid wrecked the BMW."
by Telegram Sam April 27, 2003
it literally means "losing my temper" or "going insane" to some degree. If you would look at the REM lyrics to the song by the same name, it makes more sense, it really has nothing to do with religion.
I was pretty much losing my religion after being forced to listen to rap music by all the freshman girls at my school.
by IrishRepublicanArmy November 18, 2003
1. a southern slang phrase that means "flying off the handle", losing ones cool and losing ones self-control. Some people also think it could mean to get laid.

2. a big 1991 hit song from the Georgia rock band R.E.M..
1. George: Jeremy has been acting funny since he polished off a bottle of Wild Turkey.
Billy: Yep, he's lost some of his religion.

2. The title "Losing My Religion" caused some confusion at first here in the MidWest.
by I Saw U2 Live Twice November 9, 2006
A southern expression for losing your temper.

Losing patience.
Losing your faith.

In someone or something.
WOOO GURL I AM LOSING MY RELIGION IF THAT THERE BOI DONT PLANT THOSE WATERMELONS RIGHT!!!!
by AlanaLii February 7, 2012
Must i really point out the obvious?!

you're losing faith in whatever bullshit u believe in.
Oh fuck, i just got hit by a truck. Thanks god - im now losing my religion
by stephanie March 11, 2005
1. a southern slang phrase that means "flying off the handle", losing ones cool and losing ones self-control. Some people also think it could mean to get laid.

2. a big 1991 hit song from the Georgia rock band R.E.M..
1. George: Jeremy has been acting funny since he polished off a bottle of Wild Turkey.

Billy: Yep, he's lost some of his religion.

2. The title Losing My Religion caused some confusion at first here in the MidWest.
by I Saw U2 Live Twice November 18, 2006