Cross-Thumbing is a technique developed by Dr. Mark Ringwald PhD. and Dr. Nick Pollack PhD. at their video gaming ergonomic laboratories at Brandeis University. The technique is mostly applied when playing the Nazi Zombie segment of "Call of Duty: World at War". The technique consists of controlling the right thumb stick of an XBox 360 controller with one's left thumb while the right thumb is occupied with pressing one of the four buttons above the right thumb stick. The crossing over of the left thumb across the center of the controller, and in said gaming application is most useful while rebuilding barriers in the zombie level's windows to slow down the flow of zombies in the house. The technique allows the player to repair said barrier as well as aim and dispatch targets within the level.
Drunk dude: Im too pissed, its never gonna work
Female: Cmon work with it otherwise ill fuck your friends Drunk dude: Well alright ill try thumbing in a softie.
Someone who cheats while playing "Guitar Hero" by placing a rubber band around the green button, limiting the number of buttons one needs to press, in order to obtain a higher score on the Hard or Expert difficulties.