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down syndrome ass 

"Down syndrome ass" is a colloquial term used to describe a buttocks that appears larger or differently shaped than typical. It's often characterized by a notable prominence or awkwardness in its form, resembling the appearance associated with Down syndrome, a genetic disorder. This term is not medically or scientifically recognized and can be considered offensive due to its derogatory nature.
"Yo, check out Shawty over there with that Down syndrome ass, it's like two basketballs stuffed in her jeans, no lie."

"Yeah, she got that Down syndrome ass, it's like she's carrying a whole extra load back there, making heads turn on the block."

Bro, her booty's like 'bam!' – Down syndrome ass, making the hood go wild, you feel me?"
down syndrome ass by Brained February 7, 2024
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down syndrome nigel 

the retarded kid at in class who always had snot running into his mouth
down syndrome nigel breaks stupidity world record

Internet's Down Syndrome 

A temporary condition brought on by the lack of internet connectivity and characterized by irritability, fidgeting, lack of focus, a general feeling of helplessness and occasionally exercise.
Steve: What's up with the glazed look on Meredith's face?

Brad: Well, she likes to start her day reading Perez but we have no connectivity and slipped into an acute case of Internet's Down Syndrome.

chow down syndrome 

a portmanteau of the words "chow down" and "down syndrome," meaning the loss of mental acuity following a hefty meal; aka food coma.
Is he alright?

He's fine. Just a bit of chow down syndrome.

system of a down syndrome 

being completly obsessed with system of a down
dude he has system of a down posters all over his house i think he has system of a down syndrome.

delta down syndrome 

A name referring to the fight group known as Delta. This is used when describing any flight in a JROTC unit. It can used to describe any flight or group regardless of the actual flight its self. Can be used when singing degrading songs while marching. This is only used if and when a flight is made up of complete idiots, and at least a quarter of the flight has a form of Down syndrome.

Post traumatic Down syndrome 

When some is saying some really dumb shit and you need them to shut up
Guy 1: bro what’s Obama’s last name?

Guy 2: you have post traumatic down syndrome if you don’t remember Obama’s last