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The acute onset of paranoia in otherwise normal people in reaction to the policies, the statements -- nay -- the very existence of Barack Obama.
Obama's positions better reflect the change and new direction that the American people have been calling for, but those with Obama Derangement Syndrome would rather stick with failure than even consider voting for him.
by ptulsa May 16, 2008
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Characterized by his hero worshipping of Donald Trump, along with their idealism that their idol can do nothing wrong.

When confronted their disorder manifests into petty insults towards anyone who questions their idol.

They believe this type of demoralization helps justify their stance.
Jack: Trump is screwing shit up some more.

Bill: No he isn't. He has all the best moves. You don't understand he is playing 3d chess. You leftist are pathetic and just hate him.
Jack: Did you actually read the article... here to blindly defend Trump again? Suffering from Tripple D, Donny Derangement Disorder.
by Brash Chaos May 20, 2019
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A mental disorder characterized by disparaging anything Elon Musk does. Sufferers experience rapid onset of EDS (Elon Derangement Syndrome) when they learn Elon Musk does not have a radical left-wing intersectional queer critical race theory based world view.
He hates SpaceX ever since Elon Musk began defending free-speech, he has rapid-onset Elon Derangement Syndrome
by Richard D Cranium May 18, 2023
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The irrational belief, despite all factual evidence to the contrary, that President George W. Bush has been truthful and successful in the execution of his policies, and that his actions are in the best interests of the United States.
That Iraq had developed weapons of mass destruction; that Iraq supported Al Qaeda; that the invastion of Iraq has made America and the world safer from terrorism; that his tax cuts help the middle class.
by jmeckler November 6, 2004
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(also P.D.S.) the compulsion of some Republicans to go completely nutso over any comment on or criticism of Sarah Palin and a tendency to blame Sarah Palin's mistakes on other people.
Did you see how Michelle Malkin freaked out about that lipstick on a pig comment? It was classic Palin Derangement Syndrome.
by DrMomentum February 18, 2009
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derangedmitskiaddict

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(previously catboy_epicurus)

a niche underground internet micro-celebrity, a girlboss who wears baggy clothing not in a billie eilish way, but in a hyper-attentive anti-social nihilistic modernist absurdist trendsetter trailblazer way

loved by all of her followers (not really) (wait no i meant yes really) (help she has a gun to my head)
i was pegged by derangedmitskiaddict last night, it was amazing
by junetheradical July 20, 2021
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detanged

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When someone derails the conversation as well as takes it on a tangent (OL & SD & DR*2)
Pat interrupted the group and detanged the conversation.
by SD & OL May 17, 2019
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