Synonymous with "Epic Fail", except there is no second chance. By committing this "Fatal Ouch" you officially suck, and have no second chance to redeem yourself. You're stuck sucking at life forever.
She just posed nude on the cover of playboy... and she's 450 pounds. Fatal Ouch- good luck living that one down.
"Hey dude, did you see that fatal ditzo yeasterday?"
"Yeah, he was sticking his hand up a vending machine, and then the vending machine fell and crushed him to death."
"Totally straight out of the 'darwins"