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Colombian NyQuil 

Instead of swallowing an ambien for sleep, you crush it into a nice powdery line and snort it for instant effect.
Guy 1: Hey man I have to go to sleep like right now. I have to be up at 6 for work.

Guy 2: Do you want a shot of whiskey to fall asleep faster?
Guy 1: I’m way ahead of ya. I’m taking a Colombian NyQuil . Be out in a minute
Colombian NyQuil by Les Carroll August 31, 2020

texts from last nyquil 

the act of texting after comsuming a large amount of Nyquil.
"You were crazy talking last night. Do you remember what you were saying?"

"No, they were texts from last nyquil."
texts from last nyquil by mister j October 27, 2009

The Fabled NyQuil

“Used specifically for putting a person to rest permanently or temporarily, the choice is in the user’s hands of this fabled technique. People that use this technique suffer severe or fatal injuries after if their bodies cannot handle it’s immense power.
Person 1: Did you hear what happened to Andrew?
Person 2: No, what happened?
Person 1: Mikey hit him with the “Fabled NyQuil” and knocked him into the sun.
Person 2: Poor Andrew, I bet he’s probably waiting in line at the Heaven Gates.
The Fabled NyQuil is a technique of which is forbidden in some places due to it’s destructive nature to those who wield it and those who are attacked by it.
The Fabled NyQuil by Junohh January 3, 2021

White NyQuil

Sperm, seamen, cum, and the list goes on
23:32 fatbottmedgal: I can't seem to find the NyQuil... *pout*
23:33 chains1872000: i have some white nyquil to inject in you....
23:34 fatbottmedgal: mmmm oh is that so *blush*
23:34 chains1872000: hehehe, yes ma'am
White NyQuil by alester starr November 1, 2008

Irish NyQuil

I'm gonna get tore up off of some Irish NyQuil
Irish NyQuil by TheBaldOneMpls October 20, 2004

homemade nyquil

When you can’t fall asleep so you bust a fatty in order to go to bed
Dude last night I couldn’t fall asleep so I took some homemade nyquil!