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When you're high off ecstacy pills.
for those who don't know ecstasy is an illegal drug usually taken at raves.
person 1 : are you on e ?
person 2 : yeaah man. im so murphed right now!
MURPHED by ellejhay June 1, 2006
Murphing, murph,murphed. is also known as an Irish Good Bye. To be engaged in a gathering of friends and suddenly disapear for the night with out ANY good byes
Hey Kim have you seen Ken! No he was just here, he might have murphed!
Murphed by Ktcb123 May 20, 2015
To be a nasty ass hoe, fugly as hell,and a sloppy drunk
1) Damn this hoe just got murphed.
2) Yikes! this hoe is acting a murph
3) Yo I almost just threw up this girl is a straight up murph.
murphed by rockawaygirls April 26, 2012
1. To be stricken with an exceptionally potent case of Murphy's Law

2. To be repeatedly stricken with cases of Murphy's Law, of any severity
Man, I got murphed hard when I bent over to tie my shoe, and accidentally farted just as a hot girl walked by, and fell face-forward in front of a speeding Vespa!
Wat it dookie my ninja?!?yall see that suckel at da club get murphed da fuck out?
Murphed by in4red September 27, 2006
A term used during a hand in the card game Texas Hold'em when you currently appear to be ahead in the game, and when the last card is turned and your opponent went from having virtually no hand, to the winning hand. You had just gotten murphed
OMFG MAN!!!! Your 2 pairs just got beat by the river card. It gave your opponent a straight!!! YOU GOT MURPHED!!!!!!!!!!!
murphed by murphdiggity February 3, 2010