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answer the call of nature 

an evacuation of waste matter from the body.

Often described as:
Taking a piss or taking a shit
Bob: Excuse me I need to answer the call of nature.
*Bob gets up and walks away*
Jim: (to George) Where is Bob going?
George: To take a piss he said.
Jim: You sure he didn't mean take a shit
George: I could give a fuck less Jim.
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The Call of Piskers 

In order to complete this action, the use of a 2 way radio is needed. It takes place when you are absolutely frightened (and not sure what the hell to do) and afraid of getting locked in a closet, you radio for help by screaming for your shift supervisor.
Evan: Dude, did you hear what happened last night?

Chuck: Yeah, I heard there was The Call of Piskers.

Evan: Yeah, he got tied to a chair this time.
The Call of Piskers by mmg2011 October 14, 2011

the call 

when you are doing something and you either get a call from the police or hospital that your friend has committed suicide
mom: "what's wrong honey?"
you: "I just got the call"
the call by depressed_kid101 January 30, 2021

The callmecarson effect 

Calling someone a pedophile when they date someone whos one year younger than them.
Callmecarson dated a 17 year old when he was 19. People labed him a pedophile. Now everyone on Twitter calls a one year age gap pedophilia
This is The callmecarson effect

doing the calypso 

Getting really high.
Getting so high that you refer to yourself as a sea goddess.
Raheem: Your face is five different colors right now.
Meredith: Damn, boy, have you been doing the calypso?

Raheem: I am Calypso, goddess of the sea. Let me read your palm, then you can give me some magic herb.

The Calling 

An American rock band consisting of two talented & not to mention hot people - Alex Band & Aaron Kamin.

They're most famous for their song "Wherever You Will Go" which was a big hit in '01.

Fantastic band who incorporate meaningful lyrics into their songs.
The Calling's music is just incredible!
The Calling by K o k o [Dyn] January 11, 2006

The Call of Duty Effect

The phenomena surrounding the 2007 through 2010 (RIP Infinity Ward) video games belonging to the Call of Duty franchise in which a player can be "raping ass", as players claim, in one particular game, but in the very next game, they themselves get sodomized from substantial cockiness during the latter game and end up with a shitty score and a sore coccyx.
Chad: Yo, I was totally "raping ass" in that game of Search on Crash, bro.

Jason: Yo, sick. What was your KDR the match after that one?

Chad: Yo, I got bro-raped and ended up with 2 kills and 35 deaths, bro.

Jason: Dawg, that's just the Call of Duty Effect, no sweat. Go hit up some Pabst Blue Ribbon and we'll get that KDR up.