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After you flush something down the toilet, you poop as if you want to chase what you have just flushed down moments ago. This poop is referred to as a "chaser".
(Mr.Krabs flushes Plankton down the toilet)
Plankton: I'll get you Krabs!!!! glub* glub*
Mr.Krabs: Heh Heh, and now for the chaser.
chaser by The JoshMeister101 June 15, 2009
A substance that is mixed in with drugs during preparation before seller them on the street to not only weaken them but stretch the amount of drug available in order to be sold to more customers and make more money.
The buyer rarely has any way to measure how much drug they are actually getting, it also poses a threat because they could be getting more drug than used to in addition to dealers chasing with more harmful substances or other drugs like angel dust.
Heroin and cocaine have been known to be chased with crushed aspirin when sold in powder form since it matches, the buyer rarely has any way.

"She took the smack straight from the cooker without a chaser and overdosed."
chaser by CI_grl March 24, 2008
to run after a the female sex.
"Hey I finally caught Didi!"
.."You did?"
"Yea man I had to chaser all over the fuckin place, but I caught her!"
chaser by Punkhead May 31, 2005
redneck who generally resides in a john deere tractor smoking marlby lights
chaser is drunk in the tractor again
chaser by cooter john February 1, 2004
Short for ambulance chaser, used to refer to ill-regarded and generally immoral personal injury attorneys.
Chasers flock to birth injuries like flies to a tragedy.
chaser by Magnanman August 29, 2005
when the blunt is rolled shitty and it starts burnin down the side
damn kid, this dutch is chasin like a motha fucka. learn to roll
chaser by BC money shot June 24, 2005