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Don’t Give A Shit 

It means that you are not interested in or worried about something or someone; that you place no value on something, an event or a person; that you do not care and are uninterested. It means that you place less value on it than you do on a turd, says it all really.
“Malcolm had a hissy fit when he found out he wasn’t invited to your birthday bash.”
“I don’t give a shit.”

No one gives a shit 

When you really really want to emphasize that no one cares about something. Not only does it feel satisfying to say, it's a quick and easy way to shut someone down when they say something stupid or trivial.
Guy 1: My favorite color is white.
Guy 2: No one gives a shit.

It don’t make a shit 

Southern US phrase meaning "It is irrelevant" or "It does not matter".
It don’t make a shit if you want to pay taxes. Taxes are inevitable.

I don't give a shit 

We say or use this phrase when we don't care or are not interested in what someone says or does.
Bryan:guys,i have bought a new car

worth 7 million.
Ryan:i don't give a shit about your car.

File That Under Who Gives a Shit 

This is a reply that you give to an announcement that in inconsequential, especially when the person making the announcement thinks it's some sort of big deal, or even notable.
You won a Golden Globe for that? Yes, I did. Wow...file that under Who Gives a Shit
Word of the Day on June 23, 2011

flipping a shit 

To get estremely excited, upset, or angry. Basically a more inappropriate way of saying "flipping out".
When my dad found out I scratched his car, he flipped a shit.

My girlfiend was flipping a shit yesterday when I came back late from work.

I heard Blink on the radio yesterday. I was flipping shits all over the place.
flipping a shit by starstarfairy September 1, 2009