Tweaker 

1. A person that's like a hoe

2. Some one who will talk to alot of females/males at once

3. Some one who's addicted to drugs

"Yo, you a tweaker for real"

"shut up tweaker!!"

Tweaker by Philly Girl_14 June 19, 2009

tweaker 

1. A person who customizes an operating system, a.k.a. MS Windows or Linux.
2. A person who speeds up their computer. See also overclocker.

1. You know Ken, always changing his settings. Such a tweaker, really.
2. Hey, that Dave guy burned out his CPU again, tweaked it too much.

tweaker by Toba September 22, 2004

tweaker bowl 

All night bowling alley. Usually frequented by tweakers. Using a lot of methamphetamine or tweak will cause the idea of all night bowling to be attractive.

Dude I'm so fucking wired, lets go to tweaker bowl and watch the twigs trying to roll strikes.

tweaker bowl by yobkcis June 25, 2004

tweaker 

Someone who constantly worries about a situation and obsesses over the possible outcome of something before it happens. Someone who thinks a lot and dwells on things a lot.

I am worried about how my dress will fit, will he think I am fat?

Do you think I will get in to trouble? I am tweaking on the situation.

What will happen if the judge sends me to jail? I am a tweaker.

tweaker by kelsmaster August 9, 2009

Tweaker 

A word used popularly in Philadelphia, Pa to describe female dogs who get “smutted” around by a group of men. The men are either friends, cousins or even siblings maybe complete strangers but that's rare with Tweaks. Tweakers are often exposed on the Tweaker List page via Facebook. Tweakers are not aware that they’re tweakers, until they appear on the Tweaker List. However, 99.9% are still in denial after being featured on every list. You can always find a Tweaker on Broad & Olney, King of Prussia, and Franklin Mills. They're in there like swimwear.

Girl: I'm not a tweak, I'm 15 years old and I let 5 guys hit.
I only sucked 14 dicks this year. Yes, I'm on the tweaker page, but these girls just hating on me because I had sexual intercourse with their boyfriends.

Boy: Your the true definition of a tweaker.

Tweaker by Never Lying October 13, 2010

tweaker 

a person who has lost life. they say it can kill you the first time you try it...if it doesn't you will wish it had.

The most prettiest girl in school got caught up in tweak...she isnt so pretty now and she is really mean with big gashes in her face from picking at it and no eye brows cuz she must have got really bored and tweaked by herself...poor girl she will never be the same

tweaker by I dont care how they do it February 24, 2005

Twerked off 

The act of being brought to orgasm whilst a woman twerks with a man's erect penis inside of her.

He had to tip the stripper extra because he wanted to be twerked off in the champagne room.

Twerked off by Squirt School November 27, 2013