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Crackhead tweaker 

What happens when you combine a crackhead and a tweaker, they are the most dangerous humans to ever walk on the earth. They are very unpredictable, have Usain bolt speed, and generally act feral. they are most likely addicted to atleast 4 different drugs. They have viciously long nails and lemon yellow teeth. They can sniff out drugs from miles away, if you have ANY sort of substances they want, you better give it to them or you will get mauled.
1. "Ayo what's that crackhead tweaker doing over there? Oh, he's scavenging for a grain of cocaine."
2. "You better give that crackhead tweaker you pills or he finna maul you"
Crackhead tweaker by STL446 May 20, 2023
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Is That A Tweaker 

A game residents of Terre Haute, Indiana play while driving through town. When you see someone you have to ask other people in the car, “Is that a tweaker?”. If you just guess yes, you are likely to be correct 75% of the time.
Turn on Locust Street, go a few blocks and when Donnie yells, “Is that a tweaker?” you’re in the right place.

What is that guy doing? Is that a tweaker?
Dude i'm so twerked.
Twerked by twerkin er day July 3, 2011
When one's eyes roll to the top of their head
That kid's eyes were so twaked, he must have been so thizzled.
twaked by Konck1 January 13, 2008
a tweaker is someone who has been doing Crystal Meth for a while and feens for it and is always twitching. Some one who is an addict for Meth.
L. - damn nigga YU're girl is a tweaker aint she?
P. - Ya im going to drop that bitch soon, she fucking up and be doing too much for the dopey
L. - oh, yah how much, give her my number in that case.
tweaker by baddxbxtchxdopey August 7, 2010
when one is on an upper and wants to F everyone up, full of energy
Dam fool i'm hella twaked
twaked by leo December 15, 2004
a female that is a whore or has multiple sex partners. Originated in Philly; used in Philly and parts of Delaware.
Jon-ayo she a tweaker. da whole crew hit dat!

or
Jay-yo why did u and yo girl break up? she was fine!
Jon-yeah she was fine but she was a tweaker
Jay-aw man!
tweaker by lilmamapullin April 2, 2010