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10 and 2 

The rotation of a methamphetamine pipe as you smoke it.
"If you want a good hit, rotate from 10 and 2."
10 and 2 by Cuntstina July 3, 2019

10 and 2 

10 and 2 is the rotation of smoking a methamphetamine pipe, but only while it is in someone’s butt.
Yo, you tryna do 10 and 2 tonight?
HELL YEAH I’m tryna do 10 and 2!
10 and 2 by Gang gang 123444444 August 14, 2019

10 and 2 

A band from south jersey whose name pops up in everyday life. No matter where you go there will always be something that presents these 2 numbers. You can not escape it, nor can you escape the anger that comes with realizing you've been subjected to them.
Dude 1: Excuse me, could i get a 10 and 2 5's for this.
Dude 2: Aww man are you serious? 10 and 2 I fucking hate you.
10 and 2 by d00fal00f July 7, 2010

Hands at 10 and 2 

While slow dancing or hugging someone your hands are positioned at their shoulders.
Guy: Hey do you want to dance??
Girl: Ok but keep your hands at 10 and 2

New 10 and 2

Driving with 10 fingers and 2 hands at the top of the steering wheel
Seen this girl driving the new 10 and 2
New 10 and 2 by Joe man March 24, 2024
A common phrase for a blowjob. B being the 2nd letter of the alphabet and J being the 10th.
Hey baby, how bout a 2 and 10!
2 and 10 by yomamamofo November 9, 2009