Mustachole Share definition Flag A guy who is growing a mustache but clearly has no business, as it's patchy, uneven, or just fucking ugly. Usually a hipster. I hooked up with a mustachole last night. Filled with regrets. Mustachole by BoxJohnson September 15, 2012 0 0 Get merch Get the Mustachole mug. Buy Now — $32.95 See more merch