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A word to use if you're sick of taking the time to say motherfucker. Plus it just has a better ring to it, and is superior to the crappy gangsta version mofu.
Scenrio with motherfucker:
Some asshole cuts you off on the highway. You lean out the window and yell "MOTHERFUCKER!" at him and by the time you finished yelling motherfucker he has thrown a tire iron at our head, knocking you out, and you crash and die.

Scenrio with malfuck:
Same thing happens on the highway. You lean out and yell "MALFUCK!" and have time to squeze back into the window while a tire iron goes zooming past your head. You run the son-of-a-bitch off the road.
malfuck by Izz The Frizz January 14, 2008
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MailFucked 

When you get spammed via email, text, or any form of online communication from any unwanted person and/or online company.
I hate getting mailfucked by relatives on facebook.

I just got mailfucked again by a groupon coupon offering me 20 percent off some shitty wine rack.
MailFucked by ThaChaz April 26, 2011
Related Words

Manfucked 

Manfucked

When a man refuses to allow a woman to fix something, even though he fully knows she is capable, and completely fucks up the job himself.

Being so insecure that even if you have never touched a power tool hand tool in your entire life, and a woman has built a porch or remodeled a bathroom singlehandedly, you still need to take the tools from her and proceed to fuck the job up. Then, pretend like “It is OK” and “It will work”, even though you know damn well you completely manfucked the whole thing. Simultaneously acting like she should be appreciative of everything you have done and expecting praise. When in reality, the woman now needs to fix a bigger problem or re-purchase the thing you were trying to “fix” for her as it is irreparably broken now.
I was rebuilding a hard drive and my co-worker came over and manfucked the whole thing. Now I cannot get the case off because he put the screws in “at an angle” somehow and the heads are completely threaded.
Manfucked by WhatRUKiddingMe May 27, 2018
As said by J-Roc on "Trailer Park Boys", a mafucka is the urban bastardization of motherfucker (q.v.) however its use can vary widely, see example:
"Game's postponed because no mafuckas can go to Canadian Mafucka and get a new orange mafucka for $2.99 !?"
mafucka by J-to-the-R-O-C September 1, 2005

mapfucked 

When you are playing a videogame and die because the map fucks you over into death, unwillingly
I was playing Temple Run and I got Mapfucked
mapfucked by goestoohard December 1, 2011

Malfucktion 

when the condom a guy is using breaks and his woman gets pregnant by accident.
Nicole wasn't ready for the malfucktion... now she is caring for twins.
Malfucktion by B*duB July 6, 2008
Short OG way of saying motherfucker, often used by J-roc from the Trailer Park Boys.
Man throwin' a molotov at the po-po you's a crazy mawfucka!

Check that mawfucka messin' shit up.
Mawfucka by Crazy MF August 19, 2011