mother of god Share definition Flag If something unbelieveable happens or is so unexpected and you cant believe your eyes, you can then say 'Mother of GOD!' MOTHER OF GOD!... (said a man after seeing a 24 foot pussy with legs walking towards him) mother of god by Nick November 9, 2004 0 0 Get merch Get the mother of god mug. Buy Now — $32.95 See more merch