A route of administration for a drug, examples, Actiq (fentanyl transmucosal system) and Saphris (asenapine sublingual tablets)
Buccal administration works as follows:
1) substance is introduced to the cheek/gum region
2) the substance is absorbed by the membranes
3) the substance goes into the bloodstream
Actiq, by the way, is a lollipop looking thing that delivers fentanyl to your cheek and gum membranes slowly.
Also, they taste good (about 2 grams of sugar plus flavorings per pop)
Fentanyl is an opioid and asenapine is an atypical antipsychotic.
Sources (these are safe links):
www.actiq dotcom
www.saphris dotcom
en.wikipedia dotorg/wiki/Buccal_administration
Buccal administration works as follows:
1) substance is introduced to the cheek/gum region
2) the substance is absorbed by the membranes
3) the substance goes into the bloodstream
Actiq, by the way, is a lollipop looking thing that delivers fentanyl to your cheek and gum membranes slowly.
Also, they taste good (about 2 grams of sugar plus flavorings per pop)
Fentanyl is an opioid and asenapine is an atypical antipsychotic.
Sources (these are safe links):
www.actiq dotcom
www.saphris dotcom
en.wikipedia dotorg/wiki/Buccal_administration
"Buccal administration works very good for medications that asborb poorly when swallowed or ones that cause discomfort, such as melatonin."
by jacrispy vulcano is my mom June 30, 2017
Get the Buccal mug.This kid is about 25 y/o, yet constantly makes fun of other people for being grown and on the internet and stupid, even though that's exactly what he does. He always calls his videos "satire" when it's actually a flimsy, shit excuse to not get hated, even though he still makes fun of autistic kids. He always words his insults in a way that usually it's considered an anti-insult, as Ian from iDubbbzTV says. He has a disgusting, poorly-formed chin that he constantly hides while he insults other people who are likely more everything than he is because he is an absolute pussy. All of his videos are stretched out longer than they need to be as well, so he can get more money. Speaking of money, he has a gay ass merchandise store where he sells bleach jokes on clothes, which are still hilarious and super-duper funny, if you have an IQ under 70. He's completely irrelevant by the time you're reading this, as RiceGum would say. Surprisingly, this fucker still has 4.3 million subs, but it's just that no one cares. Likely, he currently makes videos at the rate of five a day in an attempt to catch up with his subs in terms of his shitty view count.
Also, if you look hard enough, you can find his chode and asshole on the internet, not a joke. He even confirms it himself, pretty ballsy, so we can at least give him credit for that: /watch?v=jAPz4iFemRI. He doesn't need more money. Well, we can all feel bad that he got what he is leaked on the internet; a smelly chode and a rotten asshole.
Also, if you look hard enough, you can find his chode and asshole on the internet, not a joke. He even confirms it himself, pretty ballsy, so we can at least give him credit for that: /watch?v=jAPz4iFemRI. He doesn't need more money. Well, we can all feel bad that he got what he is leaked on the internet; a smelly chode and a rotten asshole.
Jason: Do you watch LeafyIsHere? He's so lit.
Mike: No, what the fuck? Wasn't he popular like 10 months ago? Maybe I remember him a little bit... I don't know. He also got fucking wrecked by iDubbbz.
Jim: Yeah, dude. Seriously. He's a pussy anyway.
Jason: Well, he has a hot asshole.
Jim and Mike: What?
Mike: No, what the fuck? Wasn't he popular like 10 months ago? Maybe I remember him a little bit... I don't know. He also got fucking wrecked by iDubbbz.
Jim: Yeah, dude. Seriously. He's a pussy anyway.
Jason: Well, he has a hot asshole.
Jim and Mike: What?
by jacrispy vulcano is my mom May 19, 2018
Get the LeafyIsHere mug.An atypical antipsychotic is a drug used to return individuals with psychotic disorders (schizophrenia, bipolar disorder, major depressive disorder {when used with antidepressants}) back into a normal or sedated state.
There is no generalization for how these drugs work, but they mostly focus on dopamine and serotonin activity.
Examples include:
Zyprexa (olanzapine)
Seroquel and Seroquel XR (quetiapine)
Risperdal (risperidone)
Abilify (aripiprazole)
Clozaril (clozapine)
The image is the 3D structure of olanzapine free base (meaning no modifications to the molecule such as in quetiapine's fumaric acid salt, quetiapine fumarate.)
There is no generalization for how these drugs work, but they mostly focus on dopamine and serotonin activity.
Examples include:
Zyprexa (olanzapine)
Seroquel and Seroquel XR (quetiapine)
Risperdal (risperidone)
Abilify (aripiprazole)
Clozaril (clozapine)
The image is the 3D structure of olanzapine free base (meaning no modifications to the molecule such as in quetiapine's fumaric acid salt, quetiapine fumarate.)
by jacrispy vulcano is my mom July 04, 2017
Get the atypical antipsychotic mug.An adjective used to describe someone on an amount of Xanax that is clearly too much for them.
Being "barred" entails slurred speech, believing you are sober, unable to walk right, etc.
Being "barred" entails slurred speech, believing you are sober, unable to walk right, etc.
Mike: "Dude, Jason got fuckin barred last night."
Jim: "Really? Well, fuck, yeah. I thought the dumbass drank too much."
Mike: "Being barred is fucking cool if you do it right."
Jim: "yep."
Jim: "Really? Well, fuck, yeah. I thought the dumbass drank too much."
Mike: "Being barred is fucking cool if you do it right."
Jim: "yep."
by jacrispy vulcano is my mom August 08, 2017
Get the Barred mug.Ibuprofen is a nonsteroidal anti-inflammatory drug.
Basically, what that means is it stops inflammation and fevers.
For the more knowing, it inhibits things called cyclooxegenases.
Mainly, cyclooxygenase-2.
Cyclooxygenases make things called prostaglandins; they promote pain and inflammation.
With less cyclooxygenases, less prostaglandins.
The difference is it actually fucking works, unlike other OTC painkillers like Tylenol (acetaminophen) or Aleve (naproxen).
Seriously, 400-600 mg (two-three Advils, its brand name) will euthanize a headache.
Not sure how it works for muscle/joint aches, but holy fuck, is it good for headaches.
Fuck Tylenol, that shit harms your liver.
Not sure how good Aleve works, but it probably sucks.
It is worth noting that all NSAIDs except aspirin have issues with raising blood pressure and harming the heart with chronic use, as well as digestive tract problems. This includes ibuprofen.
Also, you can make a topical medicine out of ibuprofen gel capsules.
Use only one capsule at a time until you find out the right strength.
Take one GEL CAPSULE of ibuprofen.
Break it with a thumbtack, small-pointed knife, or pair of scissors.
Pop the contents into one cup, then take some lotion.
Mix it with one kitchen spoon of the lotion.
Add 3-4 drops of orange oil to increase absorption through skin.
Peace.
Basically, what that means is it stops inflammation and fevers.
For the more knowing, it inhibits things called cyclooxegenases.
Mainly, cyclooxygenase-2.
Cyclooxygenases make things called prostaglandins; they promote pain and inflammation.
With less cyclooxygenases, less prostaglandins.
The difference is it actually fucking works, unlike other OTC painkillers like Tylenol (acetaminophen) or Aleve (naproxen).
Seriously, 400-600 mg (two-three Advils, its brand name) will euthanize a headache.
Not sure how it works for muscle/joint aches, but holy fuck, is it good for headaches.
Fuck Tylenol, that shit harms your liver.
Not sure how good Aleve works, but it probably sucks.
It is worth noting that all NSAIDs except aspirin have issues with raising blood pressure and harming the heart with chronic use, as well as digestive tract problems. This includes ibuprofen.
Also, you can make a topical medicine out of ibuprofen gel capsules.
Use only one capsule at a time until you find out the right strength.
Take one GEL CAPSULE of ibuprofen.
Break it with a thumbtack, small-pointed knife, or pair of scissors.
Pop the contents into one cup, then take some lotion.
Mix it with one kitchen spoon of the lotion.
Add 3-4 drops of orange oil to increase absorption through skin.
Peace.
My migraines acted up, but the pharmacy didn't get my prescription in time, so I just picked up some ibuprofen.
by jacrispy vulcano is my mom January 19, 2018
Get the ibuprofen mug.(adjective or adverb) (English): Combination of the words "very" and "good."
Pronounced like "good," but with a "v" ("vuh") sound.
Pronounced like "good," but with a "v" ("vuh") sound.
Mike: Dude, Jason's party last night, did you go?
Jim: Fuck no. He's a loser. I bet it was terrible.
Mike: Actually, it was vood. Smoked pot, drank smooth-tasting vodka. Really! It was vood times two!
Jim: Fuck, I missed out.
Mike: Hell yeah you did.
Jim: Well, did Jason play music vood?
Mike: Fuck yeah. He was a tight DJ.
Jim: Shit!
Jim: Fuck no. He's a loser. I bet it was terrible.
Mike: Actually, it was vood. Smoked pot, drank smooth-tasting vodka. Really! It was vood times two!
Jim: Fuck, I missed out.
Mike: Hell yeah you did.
Jim: Well, did Jason play music vood?
Mike: Fuck yeah. He was a tight DJ.
Jim: Shit!
by jacrispy vulcano is my mom May 17, 2018
Get the vood mug.An overdiagnosed, yet very real disorder that can be used by soccer moms as an excuse for their lazy ass little child to not do work or for the soccer mom to steal their amphetamines (stimulant meds for the disorder) and snort them at three in the morning.
Categorizes a set of behaviors such as inattentiveness and disorganization, hyperactivity, and potential trouble with filters in speech or actions, which is also called impulsivity, memory, and such. May last for multiple years or be until end of life.
It also allows you to see what the world is besides the boring bullshit mundane fucking "world" of """normal""" people.
When you have ADHD while the instructor of your class or your boss is directing you and you already know or think you know what they're talking about, you instantly divert your attention to something infinitely more interesting or relative to you.
Categorizes a set of behaviors such as inattentiveness and disorganization, hyperactivity, and potential trouble with filters in speech or actions, which is also called impulsivity, memory, and such. May last for multiple years or be until end of life.
It also allows you to see what the world is besides the boring bullshit mundane fucking "world" of """normal""" people.
When you have ADHD while the instructor of your class or your boss is directing you and you already know or think you know what they're talking about, you instantly divert your attention to something infinitely more interesting or relative to you.
Shit monotonous teacher: "Alright kids, you learned this three grades ago, but (insert boring, pointless, meandering, monotonous and drab speech here)"
ADHD child in head, while staring out window.: "Shut up, old cow... Anyway, I can not fucking wait to jack off tonight and also watch that new movie while or after I jack it.. Maybe video games. How about dead chicken corpses for dinner? WOO! I'll tell mom after I get euthanized and shit. Totally cool."
Shit monotonous teacher: "Are you paying attention, Tim Slim Jim?"
ADHD child: "I would be if it weren't for the fact that your lesson is shitty and boring, as well as ultimately pointless and repetitive to me because I don't breathe through my mouth."
Kid gets sent to office and gets in trouble for something that comes naturally to him, especially if it's for inattentiveness or not doing work.
People speculate that ADHD isn't real because of soccermoms and druggies.
Hoo hah, the whole world done fucked up.
ADHD child in head, while staring out window.: "Shut up, old cow... Anyway, I can not fucking wait to jack off tonight and also watch that new movie while or after I jack it.. Maybe video games. How about dead chicken corpses for dinner? WOO! I'll tell mom after I get euthanized and shit. Totally cool."
Shit monotonous teacher: "Are you paying attention, Tim Slim Jim?"
ADHD child: "I would be if it weren't for the fact that your lesson is shitty and boring, as well as ultimately pointless and repetitive to me because I don't breathe through my mouth."
Kid gets sent to office and gets in trouble for something that comes naturally to him, especially if it's for inattentiveness or not doing work.
People speculate that ADHD isn't real because of soccermoms and druggies.
Hoo hah, the whole world done fucked up.
by jacrispy vulcano is my mom May 31, 2017
Get the ADHD mug.