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This is the Italian F-bomb. Literally means to go take it in the ass. If administered correctly, it can leave the opposition in complete shock and awe. It also helps to make the Italian gesture that is synonymous with this expression, which is to put one hand in between the bicep and forearm of the other arm and to raise that arm with the palm of that hand towards yourself. Extremely effective to those who understand it.
Tommy Salami: Ay, Tony, wheis duh fuckin money you owe me from duh ting at duh place wit dat guy dee odduh day?
Tony Rigatoni: Vafanculo.
Tommy Salami: ........
vafanculo by Tony Rigatoni June 24, 2004
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ma vaffanculo 

Means fuck you in Italian. Used by many Italians to curse one another out.
"Stop being an asshole."

-"Ayy oh ma vaffanculo I'll do what I want!!"
ma vaffanculo by Mygooch May 5, 2014
Related Words

vaffanculo 

The real meaning is Fuck you.
If you want to say "go take it in the ass" you can also say "Ma vattelo a pigliare in culo!
vaffanculo by Chiara February 3, 2005

vaffanculo 

'Fuck off' or 'fuck you' in italian. It is a short form for "va' a fare in culo", literally "go to fuck in the ass" (intending "go get fucked in the ass"). Usually considered vulgar, but used often among (young) friends without offending intention. It can be shortened also as simply "fanculo".
A: "Bei capelli stamattina!" (Nice hairs this morning!)
B: "Vaffanculo!" (fuck you)
vaffanculo by Jero.Potute March 25, 2010

vaffanculo 

It's an insult. Anyone who speaks Italian as a first language will tell you that it means "Fuck off". If Italian is not your native language, then you may interpret it as "Fuck an ass" or "Fuck your ass" or any combination of "ass" and "fuck". see previous entries
Marissa yelled "vaffanculo" at me after I tried to appologize for sitting on her goldish.
vaffanculo by Audreyina October 17, 2007

vaffanculo 

In Italian, it literally means "Go fuck an ass"
Vaffanculo, testa di cazzo!!!!

Go fuck an ass, dick head!!!!
vaffanculo by milanista May 4, 2004

vaffanculo 

"go to do an ass" or "go to do in ass".....
But the real english translation is "Fuck you off", or may be "fuck you" i mean letterally. I say this from my 35 years old of REAL ITALIAN vaffanculo experience!.
Now other examples below..
Fuck you "fottiti"
Fuck Off "vaffanculo"
Fuck You IDIOT "vaffanculo idiota"
You piss me off! "mi hai rotto il cazzo"
Fuck you around "Vai totalmente-complessivamente a fare in culo"
vaffanculo by arturo gatta April 21, 2009