yupsiedoodle Share definition Flag Another means of saying "Yes" "Yeah" "Ok" or "Sure". A creative way to answer in the positive form. "Did you finish your homework?" He asked. "Yupsiedoodle" She replied. yupsiedoodle by Alex Harris January 2, 2007 0 0 Get merch Get the yupsiedoodle mug. Buy Now — $32.95 See more merch