the beauty of this insult is that it is a double entendre and it can be taken in two different ways. you could either tell your friends that they have "yo momma disease" or you could say that their mom is a disease.
Jack: dawg can i get some help over here
Aidan: yo momma disease (your mom a disease)
Jack: My mom's a disease
Aidan: no, yo momma disease.
Jack: :(
by yomommadisease April 30, 2020
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