wootizzle Share definition Flag It's like saying "nizzle" where nizzle represents nigga, except "wootizzle" represents woot. See also "How Snoop Dogg would say Woot." Person 1: I just KO'ed Mike Tyson in Mike Tyson's Punch Out! Person 2: WOOTIZZLE! wootizzle by tjscott87 August 30, 2007 0 0 Get merch Get the wootizzle mug. Buy Now — $32.95 See more merch