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The best anti-depressant that I've ever tried. It can make you anxious or irritable, but it starts working WAY quicker than SSRIs. Beginning dose is generally 150 mg, treatment dose is 300 mg, and if ineffective or tolerance developed, 450 mg. It is NOT an SSRI and it does not have sexual side effects. Should not be taken by people with bulimia, history of seizures, etc.
I've been on Wellbutrin XL for two months and I feel great. I want to cut people sometimes though.
by margaretsanger December 23, 2005
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A newer anti-depressant unlike the more common SSRI or Tricyclic ones. Wellbutrin is a stimulant and works by increasing dopamine production in the brain, among other things. Is the only anti-depressant to have no sexual side effects. It is most commonly used to treat depression but can also be used to treat bipolar disorder help curb smoking or drug cravings and reduce fatigue.
He was prescribed 200 miligrams a day of Wellbutrin for his depression.
by dr. suicide June 08, 2005
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A new type of antidepressant that probably has the highest rating of any antidepressant because of its stimulant amphetamine like properties without a major tolerance buildup or addictive side effects.

Makes you feel wired all day, as if you just had 5 cups of coffee but without a crash.
I'm taking wellbutrin XL for depression and life feels good again. I also saw an increase in my attention span as well for a bonus.
by AHappyGuy^_^ October 19, 2012
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It is an antidepressant unlike all those in the SSRI family. It is known to release dopamine in someone, scientists are still undecided about how it actually works. Freaky. It also is taken as a "street" drug - taken at large doses, it creates a generous amount of pleasing side effects like living in a state of euphoria, and living inside one's own brain (like echos in someone's head). All senses are hightened like X or MJ, but there is a little more control. Hallucinations occur at an incredibly large dose. Seizures are possible at that level of dosage as well.
I took my wellbutrin today so I can live life floating along, pretty oblivious to the outside world.
by RacheLAgirl February 13, 2006
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The antidepressant that I'm currently taking. It doesn't do jack shit for me, though. It just kills my personality and makes me apathetic.
Wellbutrin doesn't work.
by not found [Error 404] June 03, 2009
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