A tweaker is someone high as fuck on crystal meth. Tweakers can have sex with their partners for days at a time. They love to clean, organize, pace, etc. Tweakers can never sit still and can only focus on one thing at a time.
That tweaker has been fucking her for 10 hours straight.
by I Love Meth October 15, 2013
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An individual who uses methamphetamine and enjoys tinkering with clocks, cars, electronics, organizing junk or just coloring a picture. They are extremely meticulous and can be easily identified by a headlamp or flashlight which is inclusive to the tweaker culture. Can usually be found in the company of shadow folk.
The tweaker moved with ninja like percission across the parking lot of his local Walmart.
by LilBunny516 January 15, 2018
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A fascinating being indeed. Mainly nocturnal creatures, although some have evolved into Day-Walkers. They emerge from hiding from your Cousin's shed out back when the sunsets to pillage for supplies. You can usually identify one of these Cro-magnon humans by their lack of front teeth, entire bodies covered in sores and scabs, and missing minimum 1 digit on either hand. Forget rational communication with these things. They stammer with unintelligible rhetoric that usually relates to Seth Rollins being their favorite WWE wrestler, the one time They had to “bitch” slap their step dad or finally...they are at the local corner store walking around aimlessly in the parking lot.

Tweakers are among the most resilient animals known, with individual species able to survive extreme conditions that would be rapidly fatal to nearly all other known life forms, such as exposure to extreme temperatures, extreme pressures (both high and low), air deprivation, radiation, dehydration, and starvation.

They can get by with out nourishment and sustenance for extended amounts of time provided Crystal Meth is in abundance. Some of these have learned basic chemistry skills in order to only blow up the house around the corner from your children's school.

The highest concentrated population of Tweakers resides in the friendly community of Wood River, Illinois. A refining town in the midwest 20 miles from St. Louis, Missouri.
Bill- What was all that commotion and ruckus down at the Rocket Shop?

Ted- A tweaker doused himself and his girlfriend in gasoline and set themselves ablaze.

Bill- oh. Sounds about right....
by UnbiasedHater19 July 25, 2019
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People who are paranoid, delusional, uneducated, and covered with oozing chemical scabs and ulcers due to the acute abuse of methamphetamine. They eventually eat scabs from one another that contain the meth that their body can't dispose of, just to catch a cheap thrill. MMMMM....MMMMMMMMM!!!
I called the DEA the other day on those tweakers down the street.
by running out of patience December 14, 2007
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Some one who does crystal aka tweak and has been up for days showing signs by talkng alot pacing around and fidgiting
"Damn Pavells A Tweaker now"
by Lisa April 9, 2004
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Methheads. Named for their twitchy, "tweaky" behavior.
"Those goddamned tweakers make me nervous to be around"
by Rokki J. Rand October 17, 2007
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Them : You’re a tweaker.
You: what is a tweaker ....
by Nosluts0187 December 25, 2019
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