Top definition
(verb) to climax, to produce large amounts of sperm

(noun) sperm, semen
I spuffed in her eye

Would you like to drink a glass of my spuff?
by Mike October 01, 2003
Get the mug
Get a spuff mug for your dog Bob.
2
Drug assisted sperm, sperm produced while under the influence of either cannabis,cocaine or ecstasy. Tends to be slightly warmer and more relieving than usual ejaculation.
Barry, don't squirt spuff on the furnishings.
by John Stevenson May 21, 2004
Get the mug
Get a Spuff mug for your coworker James.
5
Onamatapoeic; the unexpected emission of gas from a freshly talcum-powdered plump baby's bottom
'Spuff!' went the baby.
by Shneaky August 26, 2005
Get the mug
Get a spuff mug for your bunkmate José.
6
the highest level of awesome; nothing is more awesome than something that is 'spuff'
The beach on a hot summer day is spuff.
by Siram41 July 08, 2010
Get the mug
Get a spuff mug for your guy Trump.