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The equivalent of pissing shit out of your anus. For the everyday yuppie, it is more commonly known as diarrhea. For those who prefer more spice in their everyday chit-chat, it is known as the Hershey Squirts.

--Can be caused by consuming large amounts of fresh fruit or fruit juice.

Q: Why would fresh fruit cause the skitters?

A: Well, the juices found in fresh fruit contain sorbitol, which is a nondigestible kind of sugar. Large amounts of this sorbitol cause the body to attempt to dilute the sugar by bringing water from the bloodstream into the intestine. This causes your fecal matter to be more liquid in substance and form, which is in turn why one hears an interesting squishy noise when one accidently sharts. This is pretty much the reason prune juice is so flippin' awesome!

It is suggested that one's everyday diet does NOT NOT (uh-oh, a double negative) NOT (*fixed) consist entirely of fresh fruit or fruit juice.
I 'et too menny peaches and now I've got teh skitters!
skitters by Messy Bumm July 16, 2005
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Man, check out the skitters on that model. Hells ya, I love a small rack like that, son.
skitters by Sandiego Gammel July 14, 2008

pimp skitters 

An affliction pimps suffer from as a result of their poor diet based primarily on greasy street food eaten standing.
"Man, I don't know why I've got the pimp skitters today. All I had was two hot dogs, a slice of pizza, a bottle of wine, two cheeseburgers and a coke."
pimp skitters by Roast Beef July 3, 2006

Exam shitters 

When you really need to shit before your exams, because you are stressed.
Damn Kris, you seem to have a case of the exam shitters
Exam shitters by baboon_shark November 9, 2020

Shitters Touch

The ability to cause everything you touch to turn to shit ie. break it, ruin it, bugger it up in some way (the opposite of the Midas Touch where everything you touch turns golden).
Don't lend him anything of value. He's got the Shitters Touch.
Shitters Touch by yorrick hunt January 17, 2008

Skithers 

Non micro-organism Diarrhea caused by over consuming a high fiber food.
That dried fruit was delicious but I ate too much and it gave me the Skithers.
Skithers by shockedquartz August 25, 2010

Sketters 

Last night, I ate a bowl of sketters.
Sketters by mason Huse November 12, 2009