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A term to describe your best girlfriend who eventually becomes your best enemy because she may have seemed like your typical selfish, back-stabbing, slut-faced ho-bag. But in reality, she was so much more than that. Coined from the ever popular and accurate movie "Mean Girls."
Dude, why is Jenna dating Sharon's ex? I thought they were bff?
Oh she was a regina george.
Ah, of course.
by Jan OLeary October 28, 2007
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Regina George (from the hit movie 'Mean Girls') is a representation of high school girls at the very top of the social hierarchy. When being referred to as a β€˜Regina George’ (commonly a negative reference), it is highly likely you are being branded selfish, a slut, a back-stabber, a bitch, a conniving-whore, a manipulator, an officious Queen B and so on…
"that back-stabbing bitch totally thinks shes like Regina George! and yet i find myself submitting to her every command."

"Vince is the Regina George of Melbourne High"
by Taylor T March 25, 2008
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What was truly beneath the mask worn by Taylor Swift before the year 2016
See how Kim saved Kenye from Taylor. I swear I knew she was Regina George!
by kidrauhl_rickthesizzler September 04, 2016
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The meanest person you will ever meet, and also the prettiest person you will ever meet.
Girl 1: Did you see Regina George?
Girl 2: Ya, look at her she's throwing nerds in the dumpster.

Guy 1: Ooohh!! Check out Regina George!
Guy 2: She's a hottie! oh, check out that body, those hips!
Girl 1: Guys, she's so mean don't be interested in her. She's just going to stab you in the back.
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The main character from mean girls.
Also known to everyone else as a Bitch. They are usually blonde, and rude. They have what they like to call "friends" which are actually just "slaves" to her every need. Regina is very annoying and really stuck up. She will lie to your face, and talk behind your back. The usual name for a Regina George is Emma, Mackenzie, or Maddi but its best to stick with Regina.
Regina George: Where did you get your skirt it's so fetch!
Sally: My mom got it for me.
Regina George*walking away*: That was the ugliest skirt I've ever seen!!
by Mean Girls January 26, 2013
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The high schools meanest bitch, biggest whore, and the biggest shit starter. Her looks distract everyone from the real demon inside. Most likely has a hot boyfriend ( probably a jock ) everyone is nice to her because they think if theyre nice, their name wont come out of her mouth but.. the only thing that comes out of her mouth other than names is literal cum
That Regina George talked shit about my boyfriend
via giphy
by qwainbaeyonce December 12, 2016
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