To chicken out or back away from something or someone.
As from the movie "Reservoir Dogs":

"Don't pussy out on me now, they believe you, they believe every fucking word you're saying. And you know why? Because you're super cool."
by Freddy February 2, 2004
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Relating to the word "Pusillanimous", it means to lack courage or resolution. When someone "pussies out" it means they have no backbone, or lack the courage to do something.

Pussy.
"Hey man, you should come chill with us later and take some ecstasy!"
"Sorry, but I don't want to lose an ice cream scoop of my brain cells, thank you very much."
"C'mon man, don't pussy out on me."
by seplion456 February 23, 2010
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To back out of everything like a little girl, especially fights.
Al Ventry likes to pussy out of fights.
by Da Finest!!!! May 6, 2004
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When someone is too scared to perform a simple task for no other reason than the fact that they have no balls.
Terrence: So is Adam going to ask out Kirsty?
James: Nah, he's pussying out.
by urbandictionaryuser9876 November 24, 2013
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A complete douche, with no balls, when called upon to do something against the rules.
Im leaving the highschool for lunch, wanna come? Isnt that against the rules? Stop pussying out and come faggot.
by wharrgarbl September 10, 2008
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To back out of doing something, out of fear.
You told me you would let me fuck you, but you pussyed out. That's why I'm mad.
by yourmom82693 June 27, 2014
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