Laughing so hard you cease to function properly.

Comes from the original term which defines a machine breaking down by saying it's "packed up"..
Dude.. When you fell down those stairs, we just packed up.. I mean, I couldn't even breathe!
by BrainShoes July 17, 2011
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When your hair is in a ponytail
*on the phone* Jenny how does your hair look right now?

Girl you know my hair is PACKED UP
by MERCiiB00 February 17, 2009
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