It's a subtle way of saying that you can't do something in a relationship. Like when you don't have time for a romantic dinner, but only two minutes for sex.
1:
Woman: We're supposed to taste wedding cakes this afternoon, remember?
Man: Ouch! No-can-do's-ville, baby doll.
2:
Woman: Wow, that was really mean. I think you owe me an apology.
Man: No-can-do's-ville, baby doll, no-can-do's-ville.
another term for a station wagon, mini-van, or any other kind of vehicle that is targeted at the "family" demographic(also M.A.V.)
"Tactical advantages aside, the M.A.V. is top of the line for the holy warrior troop transport manufactured by the Church of Latter Day Saints Military Industrial Complex. Also great for family trips...to heathen lands."