Lysdexia Share definition Flag A humorous way of saying Dyslexia, with some stereotypical misspellings. I think George the data-entry guy has lysdexia; he can never type in numbers correctly. Lysdexia by Justin Akehurst July 1, 2003 0 0 Get merch Get the Lysdexia mug. Buy Now — $32.95 See more merch