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klinefelters 

1. Klinefelter's Syndrome: Having two X chromosomes and a Y chromosome (XXY), leading to physical defects such as being exessively tall, overweight, having enlarged male breasts, and small (2cm) testicles.

2. An extremely offensive/hilarious way of pointing out that you find a female to be unnatractive by fault of her overall brute masculinity.
guy 1: why is that chick wearing football gear?
guy 2: ugh, those are her shoulders. she's definitely got the klinefelters.
guy 1: i think i'm going to be sick.
klinefelters by truffer hoffer December 18, 2005
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klinefelter's syndrome 

Klinefelter's syndrome is a genetic disorder which means that men have an XXY chromosome set up rather than the usual XY (for a male). The XXY almost always causes feminisation of men or anti-masculinisation. Klinefelter's syndrome can be extreme or non-apparent depending on the person. Usual symptoms can be :
Enlarged breasts
Wide hips
Voice not breaking
Narrow shoulders
Long arms or legs
testicular atrophy (small testicles)
infertility
Crossdresser's would probably like to have klinefelter's syndrome so that they would look girlier.

Klinefelter's syndrome 

Klinefelter's syndrome, 47, XXY or XXY syndrome is a condition caused by a chromosome aneuploidy. Affected males have an extra X sex chromosome. The principal effect is small testes development and reduced fertility. A variety of other physical and behavioral differences and problems are common, though severity varies and many boys and men with the condition have few detectable symptoms. It is the second most common extra chromosome condition, and is named after Dr. Harry Klinefelter, an endocrinologist at Massachusetts General Hospital, Boston, Massachusetts, who first described it in 1942. The condition exists in roughly 1 out of every 500 to 1,000 males.
"What's wrong with that guy? Is he gay?"
"No, he has Klinefelter's syndrome"
"So is he a dude or a chick?"
-_- "Anyone with a Y chromosome is biologically considered male."
Klinefelter's syndrome by :O] October 31, 2007

Klinefelter Syndrome 

A chromosomal abnormality. Typically, affected cells have one y and two x chromosomes (contrast the y and x of cells in a normal male). People with this non-disorder often exhibit vaguely sinister androgyny and an independent and empirical worldview unrestrained by popular gender expectations.
That tall angry guy with the hourglass figure has Klinefelter Syndrome. He's sterile. He diverts his creative instincts toward art, vigilantee suicide missions, and hormonal spazzing. Don't fuck with him, he's wild.

Klinefelter

a man who has a small penis and big man boobs
yo nigga dat dude justin brands is such a klinefelter
Klinefelter by Joey June 6, 2004

Klinefelter

A nickname for the drink commonly referred to as "Red Bull & vodka"
Hey, barkeep! Get us a round of Klinefelters, wouldja?
Klinefelter by chagrin94 November 14, 2009

Klinefelter Syndrome 

Name after TEMS Scott Klinefelter, it’s when you’re such a stud, you completely destroy all your X chromosomes making you mentally unhinged.
Oh Scott’s got that Klinefelter syndrome and that’s why he huffs emesis bags
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