It means that you are not interested in or worried about something or someone; that you place no value on something, an event or a person; that you do not care and are uninterested. It means that you place less value on it than you do on a turd, says it all really.
Malcolm had a hissy fit when he found out he wasn’t invited to your birthday bash.”
“I don’t give a shit.”
by AKACroatalin June 15, 2017
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When you really really want to emphasize that no one cares about something. Not only does it feel satisfying to say, it's a quick and easy way to shut someone down when they say something stupid or trivial.
Guy 1: My favorite color is white.
Guy 2: No one gives a shit.
by Dictionary-Man 2.0 December 7, 2021
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A person (man or woman) who pretends to care only when it benefits his or her agenda. A phrase to describe an insincere, sociopathic person who furthers their cause using fake or false concern.
"You can't slack off all day at work and then get all Charlie give a shit when the boss comes around"

That dude could care less about this company until our investor comes around and then he's fucking Charlie Give A Shit
by Charlie gives 2 shits January 21, 2010
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Meaning don't care or does not want to give a shit
Guy1: hey I broke the xbox1
Guy2: I really don't give a shit
by -Hidden-lie- December 1, 2013
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Shailee: I googled "Who gives a shit?".
My name wasn't in the search results.

Me: Think again Shailee
by Wouldn'tYouLikeToKnow;) June 22, 2012
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The department where people actually care about your problems.
Operator: Hello
Caller: Hi, I am having problems logging in to my facebook account.
Operator: Hang on let me transfer you to the Give a Shit Department
by ericool June 23, 2011
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