ghetto manicure Share definition Flag A French manicure using Wite-Out instead of white nail polish to color the tips of the nails. I saw Trish giving herself a ghetto manicure earlier. I'm assuming she's got another cheap date tonight. ghetto manicure by g0nnaflynow April 20, 2010 0 0 Get merch Get the ghetto manicure mug. Buy Now — $32.95 See more merch