A magazine homeless people sell to earn money.
I have no home so I sell the Big Issue on weekdays to afford food.
by BigIssueGuy October 28, 2008
A magazine sold by the homeless people in the UK who scrounge off of Insane Power's tax money.
A "Big Issue" for Insane Power is Flemingovia stealing his taxes and using it to sell Big Issue so he can buy crack for his son, or something like that.
by OMG nationstates September 26, 2005
Bless you! Muttered by a homeless person when they sneeze whilst you walk by them.
"Big issue!"

"Aww, bless you! But you're not having a hanky or my hard earned pennies"
by Cardboard Carl June 16, 2003
DICK OVER 14 INCHES IN LENGTH THAT CANNOT BE INSERTED INTO WOMEN OR IT WILL LEAVE SCARS
"I just can't handle my man during sex cause he has big dick issues"
by 💜LittleOne💜 January 1, 2018