Freshman 50 is the result when you don't control yourself eating in the college. It generally means that the person gains 50 pounds after entering the college. It is a derivation from freshman 15.
"Hey Broadway, You know how heavy I am right now?"
"I don't know? Worse than fresh 15?"
"Fucking Yes! I got my freshman 50!"
by Oldpunkky March 1, 2017
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