eyyyupp Share definition Flag That sound you make when you're drunk and try to shout a sentence with the "ay" sound and "up" person 1: "EYYYUPP" person 2: "Bro did you try to say 'Hey, whats up?'?" persan 1: ye eyyyupp by Kai Akito November 19, 2020 0 0 Get merch Get the eyyyupp mug. Buy Now — $32.95 See more merch