drop a duse Share definition Flag 1.To take a massive crap, poo, poop, #2, dump, or shit. 2.Drop the cosby kids off at the pool yo B! "I gotsta drop a duse, can you hold on a bit" "sure man no prob I'll crap after you" drop a duse by local beeatch May 12, 2006 0 0 Get merch Get the drop a duse mug. Buy Now — $32.95 See more merch
