During vaginal intercourse, the penis is inserted into a woman's ass and then inserted back into her vagina; therefore, the penis takes the shit from her ass and gets it into her vagina.
Rick was so drunk the other night that his cock slipped out of what's-her-name's vagina and he put it in the wrong hole--her ass. After she complained, he put his dick back in her vagina and finished up. She got a yeast infection because that’s what happens when guys cross-pollinate.
by tonymarc May 16, 2009
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To switch back and forth between vaginal and anal sex.
I got drunk last night and let John cross-pollinate. I hope I don't get an infection!
by Hollylicious November 16, 2011
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The act of having unprotected sex with one partner and then, without showering, having unprotected sex with a different partner, thus transferring the residue, juices, and secretions between the two parties either with or without their knowledge.
Gentleman 1: "Last night I had sex with Amber and this morning I had sex with Brittany. I didn't take a shower in between."

Gentleman 2: "It seems as though you've cross-pollinated...well done!"
by XxdynoxX July 6, 2015
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The act of being stoned.. and drunk.. at the same time “cross-polled” for short
Klim: Hey! How was last night?
Kathleen: Oh man! We were suckin down beers and smoking so much kush! We were so cross-pollinated! I was so cross-polled I agreed to peg my husband.
by Cornbeefha$h May 7, 2022
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When you introduce a friend from one group to a friend from another group, and they become autonomous friends, no longing requiring your services to hang out. Not necessarily a bad thing, but can be disastrous if left unchecked.
Dude 1: Dude, did you hear that Joe was hanging with Jane now?

Dude 2: Yeah dude. I introduced them a week ago and they don't even call me to chill anymore. Serious cross-pollination.
by Soren Santos September 12, 2006
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When picking your nose, you pick the left nostril, then you pick the right nostril (with the same finger), transferring a booger from one nostril to the other.
When picking my nose, I was Cross Pollinating and accidentally put a booger in my other nostril.

Through Cross Pollination I accidentally put a booger from my left nostril into my right nostril.
by Mike Toshler April 21, 2015
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To expell flatulence directly onto the skin or clothing of another person.
He lifted the small redneck behind his back and soiled his uniform using the cross-pollination technique.
by spankmasterflash 5000 September 23, 2010
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