colon blaster Share definition Flag Type of food that will eventually cause a violent erruption in the intestinal system and the defecation process. I've got to lay off the Mexican food. Those burritos are complete colon blasters! colon blaster by Indy Sparkplug May 8, 2010 0 0 Get merch Get the colon blaster mug. Buy Now — $32.95 See more merch