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synthetically or semisynthetically created drugs that are used rereationally. basically man made drugs created in a laboratory or some clandestine drug lab.

examples include lsd, mdma(ecstacy), methamphetamine, heroin, pcp, ketamine, several research chemicals (2ci, 2cb, 2ct7, DOM, DOB, DOI, 4-HO-DiPT, DiPT, 4-HO-mipt, several pcp analogues including pcc, pce, tcp, just to name a few), and finally various pharmaceutical drugs such as dxm, benzodiazepines, and various synthetic opiods including fentanyl, hydromorphone, oxymorphone, hydrocodone etc.
I quit using chems a long time ago. Now all i do is smoke weed, and indulge in the occasional mushroom trip.
by psychonautical October 15, 2006
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Awesome, cool, or better than great
Dude, that is so chem.

Negative form: chemless
ex. You're chemless, man.
by a techie March 25, 2006
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the pasty gunk in the crevice of your ass when you do not shower for a few days

I scratched my ass, and there was chem on my fingers.

Go drink a bottel of chem you stupid asswipe.

by Kayla Thy Great January 09, 2007
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