yepperino Share definition Flag Yepperino: a word used in agreement. A variation of the commonly used word “yep” meaning “yes, I agree.” "I think this pizza." " Yepperino, man. Me too" yepperino by m5424525 May 22, 2016 0 0 Get merch Get the yepperino mug. Buy Now — $32.95 See more merch