Similar to "get lost" or "take a hike," TIWYSI is a wildly popular expression meaning "you annoy me and I want you to go far away from this place where we are standing."
Attractive middle-aged man to a group of troublemakers congregating in front of his home: "Hey - take it where you shake it!"
by Bob43 March 17, 2008
by takershaker March 13, 2008