South Bound. Used in describing direction on hiking trails such as the long trail and the appalachian trail.
I'm gonna do the long trail sobo.
by ISE91 June 29, 2008
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short for South Boston aka southie MA, a hood in boston. No one in boston and southie calls it sobo. This is a term coined by realtors to make southie sound trendy like the back by or south end. This term is harshly rejected by long time southie residents who know its a gimmick to lure in rich yuppie bastards.
Yuppie- "I'm moving to Sobo where I will buy a condo for $500,000so I will be closer to my cube downtown"

Southie Guy- "Are ya Fackin retaded its called southie, not sobo you yuppie bastard,move back to vermont"
by $teve December 27, 2006
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slang term for the drug suboxone
Jean: "Hey Wally I'm all out of heroin, can I buy a sobo?"
Wally: "One for $10 or five for $40?"
Jean: "Can I just give you a quick Handy for one? Or I'll give you a Blumpkin for the five"
Wally: "I can't part with my sobos that easy Jean. Let me give you an angry dragon and you can have half my script"
Jean: "Ok"
by sanf April 24, 2011
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