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a combination between smothering and suffocation; often used by oxygen deprived persons where neither smothering or suffocation was able to be said. commonly used in the mid-west United States.

and has no relation to "smuffocate" or "smufficate" claimed to be related to oral sex.
There were so many people in that room, I started smuffocating.
by BriannSue April 16, 2011
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