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self destruct button 

The name given to a zit on your back that you can't reach to pop, so it irritates the hell out of you.
self destruct button by O.D. Batt August 20, 2010

self-destruct day 

The evil version of taking a self-care day.

A chance for a depressed person to abandon all commitments and responsibilities to do things that make them feel terrible.

Extra points if you take time off work or miss an inportant deadline.
Person 1: "I haven't seen you since last week, are you okay?"

Person 2: "I just took a self-destruct day. I slept for 14+ hours, then stayed in bed and rewatched episodes of the US office and ate so much food I couldn't move."

Person 1: "Bro, you need to go back to therapy."
self-destruct day by psykotisk December 4, 2021

Mr. Self Destruct 

1. A button in most mad scientists' lair that both blows up their crib and causes them to fall to their knees and yell, "NOOOOOOO!" while shaking their fists at the sky in a most hilarious manner.

2. Secondly, and more importantly, A song by Nine Inch Nails that was originally the first song on The Downward Spiral but now has three kickass remixes on Further Down The Spiral.
1. NOOOOOOOOOOO! Why did I even invent that button? Why did I give such a cutesy name and put it in such pain sight?? Damn you Mr. Self Destruct! Boom...

2. boom... boom. boom. (indecipherable whisper)
boom. boom.boom.boom.boomboomboomboomboom
I am the voice inside your head (and i control you). I am the lover in your bed (and i control you). I am the sex that you provide (and i control you). I am the hate you try to hide (and i control you).
Mr. Self Destruct by Fitoflaughter December 9, 2008

Before I Self Destruct 

5th studio album by 50 Cent set to be released 9th February 2009. Features the single "Get Up".
"Before I Self Destruct, Motherfucka," - 50 Cent on exclusive "50 For President" track.

mr. self destruct 

The mechanical voice inside my head that controls me.
It takes me where I want to go, it gives me all I need to know, it lays me down it uses me up, Mr. Self Destruct

Noah; Mr. Self Destruct 

see Bitch; an unpleasant woman; the female of the dog or some other carnivore.
"Man I hope my boyfriend doesn't turn out to be like Noah; Mr. Self Destruct!"