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Abreviation for the swinger/alternative sex/lifestyle website SwingLifeStyle.
I saw your mother on SLS last night, guess that explains why you don't look like your father.
by Katty kat October 29, 2007
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Stands for 'Slit Lip Syndrome'; very common trait involving someone with a lip size equivalent to a slit or a sheet of paper; Most noticeable when lips are closed or when a person expresses a dominant grin
"Did you kiss him?"
"I did, but because he has SLS I got a lot of teeth and gums."

George Clooney and Amy Schumer are just a few celebrities who have 'SLS'.
by momopeachgurl November 21, 2016
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In Asian dramas this is Seconf Lead Syndrome. There are the two main leads that are destined to be together but you always have some poor, handsome secondlead whofalls for the main lead. While they may be winning with the main lead for a while, they almost always lose in the end. SLS applies to the either female or male second lead, but usually more sympathy is felt for a male secondlead. A lot of female second leads come off bitchy and cunning.
Friend: *crying* '"noooo, this can't be"
Friend#2: "What"
Friend: "My ship is destined to sink and never become cannon, why did I fall for the second lead"
Friend#2: "I think you have come down with a classic case of SLS"
Friend: "Not second lead syndome, nooooooo"
by Princess Pandamonium September 19, 2016
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A fisherman's term meaning "sore lip syndrome". This commonly occurs 1. When a fish is caught and thrown back. 2. When fish is hooked but gets off the hook. 3. When nothing bites in a specific area because a big shot fisherman was there recently and hooked all of them. SLS can last for a good while. Unless the fish are dumb, and you're just lucky.
Example 1. Yeah nobody will catch him again for a while. That fish has SLS.
Example 2. Aw man he was a big one too. He won't bite again because of his SLS.
Example 3. Man the fish really aren't biting today. They may just have SLS from yesterday's fishing tournament.
by IAMGONDOR April 02, 2011
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Proper noun

A boarding school situated in the middle of nowhere that only accepts guys who happen to be Catholic. The only sport that SLS excells at is soccer, being that roughly 1/3 of its population is mexican.
"Did you see how good those guys were at soccer? they must have been from SLS!"

"Did you see how well-dressed and well-mannered those guys were? they must have been from SLS!"
by The4nimal September 15, 2011
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Simi Lan Sai - Literally translated from hokkien it means what penis shit? It's an expletive that means roughly the same as "WTF?!?"
A: Dude! The chick you banged last night was a guy!
B: SLS?!?
by havok March 21, 2005
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