The feeling of loss or emptiness one has after an epic bowel movement. This feeling can be accompanied by separation anxiety mixed with a feeling of euphoria. In most cases, a feeling of "lightness" or "lightening" may be experienced.
The day after eating at that Brazilian steakhouse followed by 2 cups of coffee I suffered from Post Pootum Depression.

Last night I sat staring at the wall, feeling empty, like a big part of me was just flushed away. I think I was suffering from Post Pootum Depression.
by swivet February 5, 2010
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The feeling of melancholy, listlessness or disappointment following a particularly enjoyable bowel movement.
What's the matter Shane?
Oh nothing Sara, just a case of post pootum depression.
by Shane O'Grady August 19, 2007
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